I've never been much on multi-tools, but two years ago I bought a $30 Gerber Suspension multi-tool and carried it with me deer hunting. I found that I used it quite a bit out in the field, and it saved the day when I realized my father had purchased a bargain basement can opener to bring to the deer lease.
I've been thinking that I need to upgrade to a better, yet still reasonably priced model. The suspension model is fine, except that I have big fingers, and I usually have a hard time deactivating the lock and getting the proper tool out. I feel the pliers could be a little more ridgid, but I try not to abuse them too much either.
What does everybody else with big hands use?