Questor: I don't really know how many times you can reload a high pressure rifle cartridge. I think your practice of limiting a caase to four full house charges is a good safe practice. Some brass will begin to fail early on, after one or two firings. If primer pockets start to get loose or you start getting a shiny ring around the case web or have a hard time resizing them, it is time to toss them.
I'm one of those guys who most usually sticks to one bullet weight and one powder charge, and I don't prefer to go to max charge weights, usually dropping one half to a full grain under. Still though, the average case I use starts out as a factory round and gets reloaded anywhere from 3-4 times, depending on pressure signs. Now, that's for pressures in the 45-60K range. For something like the 45 acp, I've had cases go for up to 25 reloads, at factory sepcs and pressures, before they start getting too stretched out or the primer pockets too loose. Hope this helps. Mikey.