You didn't mention what you wanted a stout load for. For hunting whitetailed deer any 45 bullet between 230 and 265 gr traveling at between 950 and 1150 fps will work just fine. Unique will fill that need just fine in a Ruger BH. If you want to get stouter that that, I think that H110, w296, Blue Dot, or AA9 would fit into that category. Myself, I would rather have accuracy over a really stout load, unless, I am after dangerous game. You will find that you will probably try more then one powder to get a load within you parameters.