Not a big difference between the two, really. What is more important is not having a gun that recoils so hard that it makes bullet placement difficult. The key to either caliber is to use the right bullet. Todays modern, controlled expansion bullets, in high velocity rifles, is really like a caliber up-grade. These bullets allow a high velocity round to perform without bullet break-up, and poor penetration. No moose is going to walk away from a 160 grain Barns TXS out of a 7mm at about 2900 - 3ooo fps. thru the lungs. A 180 grain .30 cal. at about the same speed is just icing on the cake. I have shot one moose, with a .35 cal 250 grn Nosler, at about 2300 fps. One shot, worked perfect.
Larry