The pocket revolvers were intended to fill the same mission as their modern counterparts. I like to refer to them as "better than no gun at all".
If you know you will need, or there is even a tiny chance you might need protection, by all means, bring a larger, more powerful pistol.
The pocket pistol is for when there is little chance you will need a gun, but you don't want to go unarmed, or to allow yourself to be armed when it is important that it is not apparent that you are packing. The old "B" westerns called them "hideout guns".
The 1849 pocket was quite easy to use for concealment, and I believe the Wells Fargo version was popular for two reasons. The lack of the loading lever made for a lower purchase price, and made the little pistol even less noticeable. All pocket pistols were intended to be carried a lot, but seldom shot.
If you drill your mortise in exactly the correct place, there should be no reason you couldn't ram balls without disassembly, but I suspect it would not be easy without the mechanical advantage of the loading lever.
I think I would just sell the Wells Fargo, and use the money to help pay for a pocket model.