Any Remington Semi-Jacketed Hollow Point(SJHP) will expand as factory loaded from .38 standard pressure through .357 Magnum on deer. And it will penetrate, a whole 7" on a broadside shot, to kill the critter through the heart/lung area and put meat on the table. I can't see the .44 family performing any different. Does the expanded bullet make a difference, I don't think so. I think SWC would do the same. Why are so many people obsessed with anchoring a deer as opposed to watching it fall within 50yds, I don't know, it amazes me. If anyone CONSISTANTLY drops, meaning "dead right there", with ANY .44 Mag I want video, otherwise, it is another promotion. Puncture, deflate, exasirpate, and poke holes through both lungs with anything, it will die quick. If your projectile penetrates, and gets through, even the 246gr LRN .44 Spl, then you have a winner on whitetails. Any larger animal I have no experience so I can not comment.