JACKO: Absolutely do not use reduced charges with WW296, period.
Savage: Skeeter Skelton wrote that he used a lot of 38 brass in his 357 revolvers because 357 brass was so hard to get when he was working up his loads. When he used 38 brass in 357s only, he would take any bullet weight and split the difference between the max lpowder charge for that bullet in the 38 Spl and the max powder charge for that bullet the 357 with that bullet, using 2400 powder only, and that was the loading in his hot 38s. This is OK if all you are shooting is a 357, but if you have a 38 spl around that you could inadvertantly load some of those hot rounds into it was a formula for bad times, and Skelton wrote to that more than once.
I have used some of the Skelton loads in my 357s and they are higher pressure than the 38+Ps - they are, I am certain, much closer to the 357 pressures than 38 Spl +P pressures. 2400 was the powder, not Unique or Red Dot.
JACKO: In addition you may find that using trimmed 357 brass to 38 Spl length may cause you to 'ring' your chamber with a combination of powder residue, lube and lead, which makes it a bear to chamber a full length 357. HTH.