My 357 has digested every load I've tried in it very well, but some better than others. The ones it DOES NOT like, are those over 180 gr. I tried some 200 grain, and accuracy was poor. The most accurate was the 158 gr. semi-wadcutter with gas check, and a middle of the road powder charge. Second best were some cast bullets from an old can of my Dad's, source unknown, that weighed in at 176gr. on my scale.