You should check out 'The Cast Bullet Association'. We shoot cast in 'everything' with success.
The real key is to not use your jacketed bullet reloading experience and assumptions to choose what dia. bullet to use. For either of these calibers mentioned there have been lots of people for lots of years getting great accuracy, though of late, the .308 c/w 1:12 twist is often favored and winning in competition.
I use .310, .311 and .312 dia bullets in my '.30s'. The .308 is just too small. In each case, the largest dia bullets that will fit in a fully fire-formed case neck 'comfortably' and still chamber up and extract cleanly has given better and consistant accuracy. This also means NOT full length sizing of a fired case in the conventional sense. I use the FL sizer to ready new/used brass, but after fire forming almost always everafter use the Lee Collet Neck Sizing Die to give just enough grip to the lead bullet so it holds and no crimp. This has the added advantage of being less messy (no case lube), quick, easy and efficient.
I shoot basically wheel weight alloy bullets at about 1450fps, but others use harder alloys to almost jacketed velocities. You WILL find a combination that works. My experience is that once you get the bullet dia right (remember: 'throat dia, not bore/groove dia is key) it is hard to find a load that doesnt work in a '.30'.