I won't get into a debate concerning a 22lr or 22mag as a carry pistol for defense. I will say, that God forbid I ever have to use a pistol to defend myself again, I hope my opponent if armed, is armed with a 22lr or 22mag. as he just upped my odds at coming out on top again.
Head shots? Never considered them unless looking thru cross hairs with my finger on a three pound trigger. In a real fight, all you want, is for it to stop with you still standing. That' the real world.
My son carried his M4 when moving house to house in Baghdad, but on entry, a good ole Mossberg 500 came off the sling and the M4 went back on the sling behind him.
Head shots look real good on the screen, but when your ears are stopped up, everything slows down, and the tunnel vision kicks in, the head shot is hard to even imagine. Life just got very uncomplicated, and you will either win or lose.
You have to make the decision to stand and fight, which means you may take a round, or simply run.
You can go to all the training camps, and shooting schools you can afford, but all they can do is teach you to shoot, and a few tactics that may never apply to the situation you end up in. They can't sell you courage, and they can't sell you determination. You either have it or you don't and speculation is a pipe dream. All the bravado on forums, or in coffee shop counts for nothing.
Once you have been in such a fight, you are not anxious to be in another, because you know now what it really is, and it wasn't fun, it wasn't entertainingly exciting, and mortality is very well explained in your mind.
Most folks that enjoy, talking about, or suggest killing, haven't done any, and no, I am not pointing any fingers, I don't really know what anyone here has done. I do however, from time to time speculate.
The bottom line on all this, is handguns are a personal choice, and many THINK they know which one is best. What they ACTUALLY know, is what they like. I know what I like, and I know what I trust, and I also know what works for me in the real world. It is up to each individual to figure that out for themselves.
BTW. I'm not an expert at anything. Includin gunfightin.