Yes they work well, that load of 165gr at 2900fps is the exact recipe I have in my 30/06. It has worked with flawless perfection on all Plains game including eland and a few giraffe, although those were head shot so a .223 would have also worked on them! The point is that the 165gr bullets are deadly accurate and a great combination for the .308 diameter. Personally I have so many TSX at 165gr I would not change from what I'm using. The Hornady version has worked quite well to date