Rev:
Well...I'd say you couldn't go wrong with a Ruger. However, you will probably find just as many folks out there that swear by a Browing Buckmark or S&W Model 41. Both make fine guns.
I own a few Rugers and have put a LOT of rounds down-range through each of them. I have found them to be very reliable regardless of the type of ammo I run through them. Do Rugurs have problems every now and then...sure, but they ALL do on occasion...period. Most of the problems reported on this forum are usually ammo or maintenance releated. Anyway, I've been real happy shooting a Ruger Govt. Model Mark II with an Ultra-DOT for some time now but, I'm upgrading to a European target pistol....got the "bug" I guess.
Best advice I could give you is for you to spend some quality time at a gun shop, and handle as many pistols as you can...of various types/manufactures. Find one that "fits" you. Also, try to spend some time at a range too...that will give you a good feel for how various guns operate (or not).
Once you get a feel for what's out there, you can start narrowing down a price range for the gun and sight. You can buy a NICE Ruger/Browning, with a nice red-dot, for less than $500. If you can do without all of the bells and whistles, for much less. If you do buy a Ruger, I would budget another $75 to upgrade the trigger assy...the Rugers are a little rough out of the box.
Whatever you decide, these guns will usually put rounds through the same hole...it's usually the operator that makes the difference. Good luck with your search....
Be Safe! ...Chris