If a coyote shows up at less than 250yds, he will likely not be able to tell the difference if I chose my 221 or 223 to carry that day. The Fireball does more than it should, especially with the 40-45gr bullets, but runs out of boiler room for the heavier stuff.
Fireball is just lots of "fun", easy on the ears and barrel. Never thought I would see 3500+fps, even with 40gr pills, but that's quite easy with AA1680 or LilGun.