The "45 Swift" idea has never worked out well. According to my Hornady manual, a 185 gr .452 JHP bullet, with a muzzle velocity of 1500 fps, needs to be sighted in almost 13 inches high at 100 meters, to zeroed at 200 yards. That, is a lot of drop. Your shot would be just under 9 inches high at 50 meters. The idea of a load being "flat shooting" just doesn't pan out well with the 45 Colt. Even if you could get the bullet to 1900 FPS, you'd still be almost 11 inches high at 100 meters, and 7 inches high at 50 meters. This isn't to suggest it's not do-able, but you need to look at the big picture, and understand how much drop you're dealing with. Also, a scope with a lot of adjustment capability would be a great asset. Also, you'll need a much slower powder than Unique. Think H110/296, or even Lil Gun, and 454 cases instead of 45 Colt.