The most accurate bulllets I have tried down-range. The 150's shouldn't be much difference. It is very surprising what these bullets will do, even with a modest load. You might want to compare those loads with some hot jacketed loads at 100 yds with some lumber or something to see what kind of penetration you get.
I was shooting with a friend last year, I had hot loaded 100 gr Sierras, and 168 gr cast to try out. My scope is set for 100 yds with the Sierra. At 300 yds, I had to hold over quite a bit with the 100 grain bullets. With the 168 cast and a modest load, I was putting my crosshairs right on the target at 300 and hitting it consistently. WITH A 10" BARREL!