I'm having a Mod 700 Mountain rifle rebarreled right now...to 30.06. It will have a Shilen #2 LwtWt 24', just slightly heavier/longer than the factory barrel that came on the rifle. ( it was in 30.06 and someone had neglected it, rust/crud) I wanted a slim/trim rifle but in a caliber I can use on elk too. I "almost" picked the 6.5/06 as I have never had one. However, i have '06 ammo/cases/bullets/dies out the wazoo, ha, so decided to stick with Ol Warhorse. While I have good loads from 125 to 240, I am going to work up a load with the new Barnes 130 TTSX as my flat shooter/deer load. I like the 165/168 TSX on elk size. I have a little experience with the .280 and it is a fine round, although I think a .280 Ackley Improved is the way to go in a 24-26" barrel. It would crowd a 7mm Remamg factory load ( heck, some new .280 ammo does that already) but for targets, occasional deer/elk, a fast twist 6.5/06 on a 700 long action would be hard to beat! I never worry about shot out barrels, if I can afford to have a semi-custom rifle made up, I can always afford a new barrel, ha.