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The 100 grain Nosler Partition shoots very accurately in my .243. I use 41.5 grains of IMR 4350. I also load a 70 grain Nosler Ballistic tip load I use for predator hunting This load uses IMR 4064. These loads shoot to the same POI so I can use them interchageably in the field without scope zero issues. I live in Commiefornia so I alsohave a 85 grain Barnes TSX load. The .243 is a very cooperative caliber when it comes to developing accurate loads.