I quickly learnd you have to get to know them. The key for me was that front sight bump. I found I need not try and line it up with the hammer or anything else. Just put that front sight where you want to hit.
My latest test (mine's a magnum) was to put up a paper target and shoot twice at it beginning at 1 yard. Of course the bullets were dead on. Then I stepped back one yard, tried again, and kept doing that until the rounds were not consistently in the large bullseye, about the size of a person's head.
I found it's reliably on target every shot to 7 yards (21 feet). I don't think that's too bad considering what it is. I agree with Savage that it ought not be relied upon for a carry gun, but sometimes I do. Sometimes, if I'm mowing the yard or going out on a weekday morning to get a newspaper, that's all the gun I have.
When a similar thread was up before this one, someone warmed the danger of the NAA is that we might get to confident and find ourselves carrying no other gun. I suppose that's true. It's not the best, but it's not the worst. I know it will function. It's a gun you can put your hand on in your pocket as you walk into possible trouble. Cock it as it comes out.
From tests I did with water jugs, the .22M penetrates as deeply or deeper as any centerfire pistol round; however, it does not expand. I believe it would completely penetrate a large animal's skull. I think it would certainly reach its heart.
Another good point about the NAA magnums is that they are very, very loud. If shot with one, the receiver might think he's been shot at with something much more powerful. I think he'd certainly stop bothering you and go away.
No real sound logic for carrying a weapon, I know, but points to conider. At 4.5 ounces, I like 'em.