I have used the 125's for years (actually decades , damn I am getting old) starting with my contender. The contender had a 14 " barrel and shot them great, killed deer with no problem, from 125 -150 yards. When I got a handi for my grandson to use I found it had a short throat so I had to set the bullets back about .080 and I had 8 more inches of barrel, they had to be producing at least 250 fps more than the contender. He has killed deer with it, last year he shot a nice doe at about 90 yards, did not wait for her to turn and shot in front of left shoulder, exited right hip, destroyed everything in between. Deer are just not that tough. Maybe on a hog, or something bigger.