Hi there Woodsdweller,
Not to second guess your choices here, but if you are looking for a great .22 pistol that has great ergonomics, fine trigger and in my opinion, about the best stock sites on a pistol, take a look at the Browning Buck Mark.
The Buck Mark is one of my favorite pistols and I do have the Neos, but if I had to choose between them, I would have to go with the Buck Mark. As for the Walther; I don't have one, but I think it is a neat little gun that probably satisfies a little different niche than something like a Buck Mark, Neos, or Ruger MK II.