I've only been reloading for 2 years, so believe me, I'm not an expert. However, I'd be lost without my chrony. Without it it's difficult or impossible for me to work up loads or use ballistic tables effectively. I was fortunate that I had one from my competition traditional ML days when we chronyed each load and weighed each charge and ball.
After looking at Alliant's data for a 350 gr. SP. They're running the SP at book velocity of 1481 fps with 35 gr. RL7 which would be trap door level. Your loads at velocities above that without a gas check, will cause leading. The Handi will take more. I found load data in "The Complete Reloading Manual for the .45-70 Govt" It lists a 350 gr. bullet for modern rifles, but doesn't specify cast or jacketed. Starting load 43.0 gr. RL7 for 1678 fps and a top load of 48.0 gr. for 1851 fps. I love RL7 and other Alliant powders, but I find their data limited. For example, none at all for .356 and .358 Winchester, and a very marginal selection of bullet types and weights in most calibers.
Good luck,
Pete