depends , if you live where hand loads may be a problem then look to factory loads Hornady has TAP ammo that will work . I like remington hunting ammo. The corlock with a exposed lead tip is not to expensive and should work well. If inside a neighborhood maybe a fast expanding varmit bullet as it would expand in walls and "may" not go to harm others. If the gun is for critter control as well as pure defense then a long shot may be called for and a heavier bullet would be a good choice as long as twist rate was matched .
The bullet Lloyd offered is a good choice for a do all bullet with exception of over penitration in some cases. Maybe it is factory loaded by Federal ?