I have some old Lyman moulds, Lee, and LBT but I don't cast much. Overall, I think the RCBS is a good one and you don't need gas checks. I think Midway may offer a rebate on the RCBS mould - you might want to check. I haven't cast with the RCBS but I have shot the bullet. I really like Unique for medium and light loads. I've used quite a bit of 2400 for heavier loads and H110/Win 296 for my heaviest loads. IMR or H 4227 can be very good for heavier loads too. I've played with Lil Gun some but for some reason it makes me nervous. Think I'll stick with H110 for most heavy. I've had good luck with Green Dot (light loads), Herco (med), and loved some AL8 I inherited. Search Handloader Magazine / data they put out some 41 mag loading data now and then. I like Ken Waters Pet loads for the 41 but the data is getting a bit old.