Jim, how much powder and velocity you need depends upon what you are shooting for. If it is mere target practice, use as little powder as you can get away with.
I have used 11.5 grains of Dupont IMR SR 7625 with a 173 grainer and the accuracy is superb with the recoil barely above a 223 Remington.
Currently, I use 25 grains of Reloader 7 behind a 173 grain Saeco #315 bullet. The chronographed velocity is 2011 fps. I have used 35 grains of Rel 7 with a Saeco #301 - 210 grain bullet for 2176 fps. I opt for the slower loading for accuracy and minimal recoil.
I used a Remington 742 Semi-Auto 30-06. With either of the above listed bullets and 25 grains of Rel 7 powder, it will shoot great at 100 yards. I'm not even going to post the actual group sizes. I use both loads to shoot out to 500 meters and it works great. The wind and mirage becomes a major factor, though. I have had to hold 8 feet of wind to hit a Ram Silhouette, but it was repeatable.
I think I'll pull the old 06 beast out for tomorrow mornings range session. I got all fired up.
Harold Clark