Me personaly I don't use damascus that much in the field, simply because I haven't gotten the performance out of it that I get out of my favorite, 52100. That said I'm curently useing a 1084/1520 damascus neck knife while working offshore, I'd rate most damascus knives that I've made and tested close to or maybe a little better than plain high carbon steel for edge holding and sharpening, which is plenty good enough, I just like pushing the envelope.
As far as use goes, if it was welded up right and no flaws, and properly heat treated it should make a good user, depending on the mix.
One thing that has helped my little neck knife in the salt water environment is that I wipe it clean befor putting back in the sheath, and wipe a little "nose grease" from the side of my nose or from behind the ear on the blade. I know it sounds disgusting, but it works and is not poisionus like petrolium oil is. One trick for carbon steel knife use in the field is after the first cut rub the blade down with the animals own fat, that will protect the blade from rust. It will still stain, but not as quikly and will help keep blood from rusting the blade.
Hope this helps,
Will