I'll be doing some local moose hunting this year, again, and will be using my 338 Win. Mag. and my 358 Norma Mag for that.
If I do get around and do a sheep hunt, I'll opt for my 270 WSM or my 300 RUM if it's ready by hunting season.
And if the 40 mile caribou herd is accessible this year, I'll opt for my 358 Norma Mag to take on that hunt and hope I can get a grizzly in that region (two grizzly bag limit yearly now in that unit).