Dusty...
That load sounds dangerously "HOT" to me.
It appears to me that a 27.2 grain load of H-110 in your .45 Long Colt may be a mis-print and very possibly a DANGEROUS over-load in your .45 Colt pistol.
I have shot a load of 24.0 grains of H-110 (shown as a maximum load in Hodgdon's "Basic Reloaders Manual-2003)) behind a 240 grain jacketed hollow-point in my old 3-screw, .44 magnum Ruger Super BlackHawk (7½" barrel) as a hunting load... and it's surely a "max" load in the .44 Remington Magnum.
This same load also strongly operates the semi-automatic action of my old/style Ruger .44 magnum Carbine indicating it is a powerful load. A "light" load won't operate the carbine's action properly.
The Hodgdon "Basic Reloaders manual-2003" lists the chamber pressure of a 240 grain bullet using 24.0 grains of H-110 as being 36,200 C.U.P. for the .44 Remington magnum. This same manual lists 28.0 grains of H-110 behind a 230 grain bullet as a MAXIMUM LOAD (@ 29,000 C.U.P.) for the ".45 Winchester Magnum" cartridge.
I noticed, in Hodgdon's complimentary "Basic Reloaders Manual-2003" (given away free of charge at retail gun shops), that NONE of the "maximum loads" shown for the ".45 Colt" ("Long Colt", not the "ACP)" exceed 14,000 C.U.P. with ANY weight bullet.
Another thing I noticed is that this Hodgdon-published complimentary reloading manual does NOT list H-110 as a powder SUITABLE for the ".45 Colt" in ANY bullet weight.
There's a HUGE difference betwen 36,000 CUP & 14,000 CUP. And so, I seriously question using that big load (27.2 grains) of H-110 in your .45 Colt.
In conclusion, it appears that you are RIGHT to question this load... I'd check it out further... especially since the Hodgdon-published complimentary reloaders manual does NOT list H-110 as a powder SUITABLE for reloading the .45 Colt cartridge.
Strength & Honor...
Ron T.