I like the Ruger Mark II. You have to hold it a certain way to get it reassembled, but once you know this procedure it is not difficult. The Mark II is not fussy about ammunition.
A single action revolver is more at home chambered in centerfire cartridges in my own opinion. As to the .22 mag convertible cylinder, you won't do much shooting with that due to the cost of ammo. If there is one caliber of weapon that spends a lot of time in people's closets, it's anything in .22 mag.
As to the question, how loud is the report of a .22, I won't even run a lawnmower again without hearing protection. I damaged my hearing enough as a silly youth; I need to keep what I have left. Hearing loss is accumulative, that is, you lose a little bit at a time. What you lose with each outing where you fire weapons without hearing protection you don't notice at the time. Next thing you know, maybe even years later, you are saying "What?" a lot.