As someone mentioned, if you want to see loose screws, shoot a Colt SAA. The vibration of firing causes it, and Colt has little fiber washers under the screw heads, which do little good, and Ruger used to use Nylock screws, which helped a little, but Locktite works best, just DO NOT use the Red Losktite unless you never want to disassemble again.
The first screw to loosen in the Colt is the one holding the ejector rod housing to the barrel, and that can lead to a lost screw in the dirt. This also loosens in a Ruger, leading to a sheared screw there, and one of the reasons Ruger had changed to an alloy housing. The front and rear TG screws loosen and the frame starts to rock, answer, keep a screwdriver with you with any Single action.
This has little to do with the "quality" of the gun, but to the physics of recoil, and a design that has far too many screws in it, and one of the reasons the Civil War and Indian War soldiers liked Remingtons with their solid frames, and single TG screw.