MRC - that Nosler bullet is a handgun bullet and may not give you the success you should get from the 444 loadings.
If you want to stay in that same weight range, Hornaday makes a 265 gn bullet specifically for the 444 that has worked very well for a lot of Triple 4 shooters on this forum. You can come pretty close to 2300'/sec with the 265. I don't know if the 250 Nosler would hold together at those velocities. HTH. Mikey.