300 yards is a far piece out there!!! Extremely good rests are required without a doubt. Optics are another key factor, and a shooter with very good shooting skills and eye sight. I use a 3x-12x Burris.
Now to your question...I have two 223 barrels and BOTH are M.O.A. shooters out to 200 yards. A few weeks ago, I wacked a groundhog at 273 yards (range finder verification). I have shot quite a few at the 250 yard mark. These hits are all under the best of conditions, both with the weather and the rest situation. Again, 300 yards is a far piece out there!!!
I think if you compare the 221 to the 223, the 223 will out do the Fireball. Plus, brass and reloading data is plentiful. And, if you don't reload, factory ammo is dang cheap. Good-luck...BCB