Tell ya what I found, but it was with a 10" Contender. With the 35 gr V-max, my most accurate load was at 10 Gr. of 296 (same as H110). As I went up towards 11 gr., group size kept getting worse and worse.
None of the loads with the 296 and 35 gr V-max were as accurate as 11 grs of IMR 4227 and the Hornady 45 Hornet bullet.
Know you gun might like something totally different, but I hope this helps.