I have shot an Elk with a TC 14" 35Rem/2X Leupold and Pachmyers. The load at the time was a Hornady 200 gr Spire point over a very charge of H322. I shot teh Bull at about 125yds broad-side while he was 'buglin'. At teh shot, teh dust flew off his ribs,but he just stood there. The herd spooked and he took off with them. There wasn't much blood at first, but it was easy to see where they entered the woods 200 yds away. Upon entering the woods we stumbled upon what looked like the floor of a butcher shop. From about 4' high on the tree, tothe ground, blood was everywhere, even on the trees he run over. We even picked up pieces of rib bone. He followed the herd (attempted) onto a rock slide. Guess where he died? Anyhow, the bullet broke ribs entering, destroyed teh lungs, jsut missed the heart, but cut the aorta, broke a rib exiting into the off shoulder. Total distance traveled was about 250yds, but the last 50 was stumbling and falling into trees. I really think the newer SSP's like the 180's would perform a little better. maybe not. I think the 125-150yd line is closing in on maximum distance for performance though. I did not chrony the load, but I will. It was a very accurate load out my barrel.
Good luck, I'd use it again. I think it's one of the most over-looked cartridges out there.