Heres how I would do it:
1. Clean the barrel, then shoot half a dozen factory rounds to foul the barrel. Shoot slowly, no more than 3 rounds at a time, to keep the barrel cool.
2. When you are ready to shoot the development loads make sure the barrel is completely cool before starting.
3. Shoot one group of 3 using the lowest powder charge, then let the barrel cool. This is a good time to mark your target.
4. Shoot 3 rounds of the next higher powder weight, then let the barrel cool. Mark your target again.
5. Shoot 3 round of the highest powder charge, then let the barrel cool. Mark your target again.
6. Start over again at step 3 with a fresh target and shoot the remaining rounds.
For the .243 I would shoot at 100 yards with the scope cranked up to its highest power. I would also make sure I had a good steady rest - you want to test the ammo and to the extent possible, eliminate other variables.
Last weekend I drove 35 minutes to the range to test some loads. When I got there I decided it was too windy even in the sheltered 100-yard ranges so I turned around and drove home again. If the wind is kicking up you are pretty much wasting your tme shooting for groups.