You should really look into getting some handgun experience with a .22. The ammo is cheap so you can learn how to shoot well without spending all of your money away. You don't necessarily have to buy a .22 but you should get some experience on one before you go for the big boys. As far as the .22s go, ruger, browning and others have nice models. I have a taurus .357 mag and really like it, the price is right and it shoots great. Other nice revolvers include ruger, smith and wesson, colt and dan wesson. As far as the semi-autos go, I would suggest a berretta, cz, ruger, hk or sig in 9mm or .40. All of the afore mentioned brands are roughly equal in quality although the cz and ruger models are inexpensive and straight shooters. Many would also add the glocks to that the list as they are very nice guns that are regularly used in law enforcement. I don't particularly like them due to the internal hammer and overly light wieght combined with high price, however I would suggest considering them as an option.