I`ve been loading Win-296 in mine for years. Real good accuracy and very high velosities. If you have the Serria 180 gn. bullets I would recomand you get something else to hunt with. I pinned a big doe in the shoulder joint the first time I took mine out. The shot was abt 75 yrds. and the 180 Serria failled bad. The way she was standing I should have taken out her heart, but the bullet was destroyed in the shoulder joint. I got excellant accuracy with them, and if you only shoot through the ribbs the 180 Serrias will do a great job, but don`t count on penitration through hind quarters or shoulders. I`ve had real good luck with the 158 gn. Hornady XTP bullets in this round.