Rob220Swift: I'm currently toying around with various loads out of my .45. I have no experience with deer killing performance of the different projectiles. Common sense dictates that heavier bullet would be the better deer getter. Trade off, of course, is trajectory. I thought I was dead set on using Powerbelt 195 Aerotips, but they're expensive ($1+ a piece), and I like to practice with my equipment. Since I have a self imposed limit of 100yds, I can go heavy and not worry too much about drop. Right now, I'm experimenting with T/C Maxihunters, 255grains.