as well as gun, rig, hand start position, size of target. you ever try those matches while guns were going off in your face? The outside distance at which you will fire, in justifiable self defense, is 10 ft. Most often, it will be 6 ft or less (hand over the money" distance), or rape-beating distance, grab you from behind mugging distances are very common, too. The odds are against the attacker having a gun, but the issue of this topic WAS "gunfight", so we'll stick with that.
There's reaction time, and then there's RECOGNITION interval. If you start a concealed draw, when he has no idea that you are armed, the reaction time comes OFF of your draw, and goes ONTO the armed attacker. Also, he must RECOGNIZE that you are drawing a weapon. Naturally, you will try to draw when you see that he is distracted, by your talking to him, if nothing else. A distracted reaction time is .30-.40 second, not the .20-25 second of a "keyed in" trial-run. His recognition interval can easily be the same.
From the pocket holster, starting with hand in a firing grip on the gun, it's no big deal to react, draw, and hit the chest in .60 second, with .20 second of that being the reaction time. If I start first, he has .40 second in which to react, recognize the threat, DECIDE what to do, and fire. That first shot, flying past his ear or gonads, is HIGHLY likely to make him miss. Naturally, one attempts such things only if they think that the guy is going to shoot them anyway. The defender might even have body armor on, ya know.
If he's TOLD you to "hand it over", or "let me see your hands", he EXPECTS to see your hand come out of your pocket, maybe even expects to see SOMETHING in your hand.
When I was using a speed rig, surrender start, and a 1911 in IPSC, to react, draw and hit the chest, reliably, at arm's length, in .60 second was nothing special. this was firing from the retention, one handed position, with the curve of the wrist-forearm joint slammed up into the pectoral muscle. If the target was 10 ft away, add at most another .15 second (going to an eye-level, two handed stance, point shooting. Starting with hands at sides shaves off about .10 second, too.