The things that you are seeing, shooting over your chrony, is the reason to own a chrony.
I have found that when working up a load, one essentiol step is to run them over a chrony. a high extreme spread will kill accurracy. It can all change with a different powder, bullet, or a primer. Cases in a 357 don't seem to be as critical.
One time a friend, who didn't handload, shot his 30-06 over my chrony. He got an extreme spread of over 150 fps from some Remington ammo he thought was pretty good. He did get flyers but always figured it was him and not the ammo. After that session, he decided to try some of my handloads. I loaded up some medium loads for him and he got severe case seperations and we found out his headspace was extra long. It worked fine with new brass but when I loaded those cases once more, they seperated. He got the rifle fixed and now it shoots good groups with the origional ammo.
For a 357 some of the powders that I get really good results with are:
Bullseye for cast bullets. 5 gr for any weight from 125 to 170 gr bullets will give 1400 to 1100 fps with great accuracy
Unique for medium loads. 8.5 gr under a 125 gr jacketed bullet will give 1650 fps and good accuracy from a 20 inch barrel.
H110 and W296 are good
Lil'gun. 16 gr with a 190 gr cast bullet will give 1900 fps and knock down 200 meter rams really good. 20 inch barrel.
These are just a few that I like and they were all developed with my guns using a chrony.
Sixgun