Quality on the Palmer guns varied rather considerably, and with no apparent pattern. A thorough inspection will reveal most problems.
Two specific areas to check: make sure that the crane sits flush with the frame when closed, and examine each chamber for machining marks. (There will always be some, but what you don't want are deep marks or a rough chamber. Extracting full house .445SM brass from a rough chamber can be quite difficult.)
Of course, all of the other normal revolver checks are indicated.