My favorite load has been 28 grains of 5744 with a 405 lead roundnose flat point for my Sharps and Marlin. Its accurate and has got plenty of power for any animal on this continent too, a friend of mine used this load of a buffalo at 200 yds and drop him with one shot, he told me he found the bullet in the skin on the other side! Thats good enough for me, Oh its easy on the shoulder too.