The barrel will be fitted to a SB2 frame so the firing pin placement is not a problem and the barrel will hold the pressure , what i was concerned with was keeping the chamber square with the bore , so i guess this one is off to the smith too .
the headspacing question was a concern to me, as was the idea of fitting the barrel to the frame. (i'm not one to assume so i didn't guess that you'd use an SB2 frame) personally i'd look at taking a .22 Hornet barrel and having it fitted to your present SB2 frame. then i'd chamber the barrel to a .222 Rem' if it was me. and yes, i'd do it at home by hand with a reamer cut with a proper pilot for such usage.
to each his own, however.
in any event, i see that you remembered the barrel fitting, etc. however: i'm guessing that no gunsmith does it as well as the people at NEF do. probably because they've got the fixtures to grade and assign a size to the barrels and frames when matching them. similar to what we did at Ford when figuring out which pistons would properly fit the various bores in a V-8. (there isn't much tolerance in those things!)
i hope it works out well for you.
take care,
ss'