I purchased a stainless 14" .375 Win. barrel just after last deer season. Have yet to kill anything with it. From the data I found, I have been using the 220gr. Hornady's with IMR 4198. I like the lighter grained bullet...I imagine that recoil will be greater with the heavier bullets. You have to watch bullet choice-a lot of the .375 bullets are designed for the .375 H&H, and probably will not expand properly out of the Win. as good. I believe that the Hornady 220gr. are specifically designed for the Win., they are a flat point and are fairly soft and should be deadly for whitetails, which I plan on hunting with the caliber. I have a Tasco red dot on top of it, so the long shots are not the greatest of groupings at 100, but I really like the pointability and quickness of the gun with it. Going to try to kill a whistle pig or two with it ASAP. Happy huntin'