Funny, GB & RH1, you are both partially right. Ask any of the bullet manufactures about the "required" velocity to expand a certain bullet and they will tell you. Then look at what that velocity equates to, for that bullet weight, in "kinetic" energy. That is also a part of the old axiom of: "800-1000 fpe minimum to kill a deer 1200-1500 fpe min for elk and moose." The people that said this gave others the benefit of the doubt, that, just becuase a 220 swift can churn up these energies... obviously doesn't mean it will penetrate deep enough in to the vitals with soft point ammo to reliably harvest medium to large game, but, that if you were using appropriate bullets from an appropriate caliber, these figures will let you know the maximum range at which your bullet will perform as it is intended to to make a clean humane kill.
Funny I have seen countless deer shot perfectly with high power centerfire rifles and they just ran away, it takes lucky timing and approximately 2700-2800fps min to make "consistant", drop'em in tracks, "shock kills."
My 12" .44mag dropped a charging 175lb hog with a measly 1200 fps load through the lungs, this was a LBT 280g WFN, and thats all the velocity "that" bullet needs to fully penetrate, stop, and kill a wounded ticked off boar. Hitting at 100 yds will be tougher than killing at 100 yds in this caliber.