I find the 7-08 pretty easy to load for. I've tried several different powders but keep coming back to H4895. H414 is pretty good too. I've read that some folks get good results with Varget but I have always been able to find a powder that did a better job. Whichever bullet in the 139-145gr range that gave you your best accuracy is the one I'd pick. I like 140gr Rem Core Lokt bullets as a general thing and if I want a little twinge of extra self confidence, I switch over to Nosler Partitions. Also in 140gr.
I don't try to motor my rifles too hard. A 140gr bullet started at a middle to high 2700fps or low 2800fps will kill a deer very dead.