The best American made .22 auto, IMO, is the S&W Model 41. I have had one for 20 yrs. and it is very accurate and works great.
The most cost effective American made auto is arguably the Ruger MK series. I just got a MK III Competition. Am waiting to take delivery.
If you have a 1911, there are a bunch of .22 conversions available. I have a Marvel No. 1. Very accurate.
If you have a CZ-75, the Kadet conversion is available. Nice and accurate and very reliable.
I have no personal knowledge of the other S&W, Browning, Beretta, etc. autos available.