Varget works well in the Handirifle .223; good velocity at lower pressures. H335 is accurate with smaller (40gr) bullets, but not at higher velocity loads. As the pressure goes up in a Handi, cases start to stick and cleaning won't help - the cases swell and that's that. Others may have had better luck, but that's how it's been with me. Even so, the accuracy is excellent.
OTOH, if your Handi has the extractor and not the ejector, it may be a moot point because the rifle with definitely handle the pressure.
Good luck!