The only thing that I really worry about for the autos is range, you have to be willing to go hunting, spend time to get the right shot if you are going to go with a .45acp, 10 mm, or the like. The big boys like the DE, or the rowland will extend your range, and if you expect to want to take over a 50 yard shot, make sure you have the gear to be prepared for that shot.
Maybe try some bowhunting to go along with the regular sized auto hunting pistols.