My old standbuy for deer is the 130 grain Nosler Partition with 60 grains of RL-22 or H4831. I have also used the 150 Grain Partition, but can't really tell that it killed any better or any differently than the 130 grain, at least on deer. I have only recovered one bullet. It was a 130 Grain Partition from a mule deer shot at 300 yards, broadside (measured distance with laser range finder the next day). It was rolled up under the hide on the far side of the deer after penetrating through its lungs.
My 130 grain loads chronograph at 3,080 fps in 22" barrels and 3,180 fps in a 24" barrel.
I have also taken two wild boar with the 130 grain Partition and both were one shot kills. One was a heart shot and the other was a head shot. He was quartering toward me and I led a little too far. Instead of hitting the front shoulder, as he quartered toward me, I hit him in the eye. It was weird. He dropped like a sack of potatoes at about 50 yards but we couldn't find a gunshot wound anywhere on him. Finally, the guide opened his eye and there was a bullet hole under his eye lid. My bullet hit him squarely in the eye and passed through his brain, killing him instantly. The eyelid closed over the entrance wound. After finding the entrance wound in the eye, we found the exit wound under his thick matted hair on the far side of his head.
Obviously the 150 grain bullet is probably better for elk, moose or whatever, but I use a .338 WCF for that task loaded with 250 Grain Nosler Partitions.
I have a good friend who uses 130 grain Nosler BT's over 55 Grains of IMR 4350. In his 20" barrel he only gets about 2,950 fps, but it kills instantly on lung shots and he has recovered several bullets.
The .270 is among the greatest hunting cartridges there are. In many years of hunting I have noticed that .270 shooters are usually good game shots and that 7mm Magnum shooters, by and large, are terrible. I think many guys buy magnums without realizing that the increased recoil and noise require more skill that most are unwilling or unable to achieve. Over and over I have seen guys with 7mm mag's blaze away and empty their rifles and miss every shot. In my experience, the 270 shooters do much better. Obviously guys who handload and who are "shooters" as opposed to once a year hunters are capable of good shooting with the 7mm magnums, but frankly such guys are far and few between in my experience.