Well, the reason I asked, is reading back on the past comments. I see the .257 Rob. mentioned, and nobody can take anything away from that grand old round either. Not that it's an old, old round. But, the .250 Sav. within normal hunting ranges don't give up a lot to it. Yes, be cause of it larger capcity, it does have advantages and versatility, and more so with heavier bullets. Both rounds are loaded in the manuals to modest pressure ranges, leaving room for improvement in strong action however. But when compared heads up within those parameters, the .250 only gives up 20-25 yds on average of point blank range...At least that's how I look at it.
Now back to my loads, of course mine is a AI version so my data is a moot point up to a point. I haven't worked with the 100 gr. weight much yet. But what I have done, the NBT's shot extremely well avg. .2-.3 moa. I got mine and primarily as an Antelope round, but did do work with the 110 gr Accubond for Deer. I just feel better with a tad more weight when working with these smaller calibers. It gives up a little speed at first, but has advantages when the range gets pushed abit. But being a round that's listed at 43-44,000cup range, here again, I don't hesitate pushing that up abit in a good action such as the M7 you mentioned. I don't know the strength of the original .250-3000 brass, but if it becomes a problem, one can always use the possibly stronger (?) .308 brass with some extra work.
Mine is a bit different, as in my Encore I had it chambered to take .307 brass necked down with the neck left long. I can still fire standard .250 rimless in it with a different extractor if I had to. One thing I did find however, and it likely will differ for you. When pushing it, I found it likes the slower powders.
Now mine being a single shot has some bearing on that likely, as it is throated to take the 110 gr. AB's so that it's not seated past the neck/shoulder juncture. So I do have a fair bit more capacity than standard. My COL for the 110's 2.835". I didn't have 100% load density with H4350, so I tried H4831SC, and I still have room. but sooner or later, enough is enough, and I'm getting excellent accuracy with the H4831 at 97%+ load density, with the 110's doing 2700 fps out of a 16" barrel and no pressure signs. And so far the primer pockets are still tight after 5 loadings. For Antelope or Deer it has enough for me. If for any reason I felt otherwise, I'll use the 6.5x57air or larger yet.
Dave